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Cancer cells can spread from the original cancer (the primary cancer), through the bloodstream or lymph vessels, to any of the bones in the body. Bones commonly affected by secondary bone cancer include the spine, ribs, pelvis, and upper bones of the arms (humerus) and legs (femur). Secondary cancer in the bone keeps the name of the original. Transitional cell cancer of the renal pelvis and ureter is a disease in which malignant (cancer) cells form in the renal pelvis and ureter. A personal history of bladder cancer and smoking can affect the risk of transitional cell cancer of the renal pelvis and ureter. Signs and symptoms of transitional cell cancer of the renal pelvis and ureter.